Search for predicted microRNA targets         [Go to the newest version of TargetScan]

1. Select a species    

AND

2. Enter an Entrez Gene symbol (e.g. "LIN28")

AND/OR

3. Do one of the following:

  • Select a conserved* microRNA family

  • Select a nonconserved* microRNA family

  • Enter an miRNA gene name (e.g. "mmu-miR-124a")

  • *conserved = conserved across human(H), mouse(M), rat(R), dog(D), and sometimes chicken(C)


    TargetScanS predicts biological targets of miRNAs by searching for the presence of conserved 8mer and 7mer sites that match the seed region of each miRNA.

    TargetScan Release 3.0 displays predicted regulatory targets of mammalian microRNAs. Targets are predicted using the TargetScanS algorithm and are mostly the same as those published in January 2005 (ref. 1) and presented in previous versions of the TargetScan site (Releases 2.0 and 2.1).

    This website considers matches to sites in the UTRs. Conserved targeting has also been detected within open reading frames (ORFs). A listing of these ORF sites can be found at the bottom of Supplemental Table 2 of reference 1.

    More information about Release 3.0

    Download all data


    References:
    1) Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets
    Benjamin P Lewis, Christopher B Burge, David P Bartel.     Cell, 120:15-20 (2005).
     
    2) Prediction of Mammalian MicroRNA Targets
    Benjamin P Lewis, I-hung Shih, Matthew W Jones-Rhoades, David P Bartel, Christopher B Burge.     Cell, 115:787-798 (2003).


    Links
  • Burge lab
  • MIT Department of Biology
  • MiRscan Web Server
  • Bartel lab
  • Whitehead Institute
  • miRBase
  • Bioinformatics and Research Computing (Whitehead Institute)
  • TargetScan 3.0 has been developed and tested with the following browsers: Firefox (Windows/Mac/Linux), Internet Explorer (Windows), Safari (Mac)