Archived releases

TargetScan: Prediction of microRNA targets


Release 2.1

Predicted miRNA targeting in 3'UTRs, as submitted to the UCSC Genome Browser
These are the most recent TargetScanS predictions (April 2005). They are essentially the 3'UTR targets reported in the Lewis et al., 2005 paper, with a few changes arising from updated gene boundary definitions from the April 2005 UCSC genome browser mapping of RefSeq mRNAs to the hg17 human genome assembly. To avoid difficulties in browser display, the few predictions spanning splice junctions are excluded.


Release 2.0

Predicted miRNA targeting, as published in Lewis et al., 2005
These are the TargetScanS predictions published in January 2005, including targeting in ORFs.


Release 1.0

Predicted miRNA targeting, as published in Lewis et al., 2003
These are the original TargetScan predictions.


References:
1) Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets
Benjamin P Lewis1,2, Christopher B Burge1, David P Bartel1,2. Cell, Vol. 120 (1), January 14, 2005.
 
2) Prediction of Mammalian MicroRNA Targets
Benjamin P Lewis1,3, I-hung Shih2,3, Matthew W Jones-Rhoades1,2, David P Bartel1,2, Christopher B Burge1. Cell, Vol. 115 (7), December 26, 2003.
     
1 Department of Biology, Massachusetts Institute of Technology
2 Whitehead Institute for Biomedical Research
3 These authors contributed equally to this work